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연구실 :
약학관309호

연구실번호 :
3452

이메일 :
ghim@ajou.ac.kr

연구관심분야 :
논문 및 연구활동
연구활동(주요논문)
  • [논문] 김형수, 김홍표, 노민수, 안성진, 공준표, 안성찬, 표정주, 정다람, 이주창, 황석영, 신일진, 김정민, 2-Phenyl-8-(1-phenylallyl)-chromenone compounds have a pan-PPAR modulator pharmacophore , BIOORGANIC & MEDICINAL CHEMISTRY , Vol.27 , No.13 , pp.2948 -2958 (Jul, 2019)
  • [논문] 백승훈, 이동주, 김홍표, 정혜경, Structure analysis and antioxidant activities of an amylopectin-typepolysaccharide isolated from dried fruits of Terminalia chebula , CARBOHYDRATE POLYMERS , pp.100 -108 (May, 2019)
  • [논문] 윤태종, 박상규, 류지연, 박혜선, 이한아름, 홍신희, 홍관수, 김홍표, 조은이, Lechitin nano-liposomal particle as a CRISPR/Cas9 complex delivery system for treating type 2 diabetes , Journal of Nanobiotechnology , pp.19 -31 (Jan, 2019)
  • [논문] 이동주, 김형수, 유희선, 김석호, 김홍표, DDQ-Promoted Mild and Efficient Metal-Free Oxidative α-Cyanation of N-Acyl/Sulfonyl 1,2,3,4-Tetrahydroisoquinolines , MOLECULES , Vol.23 , No.12 , pp.3223 -3235 (Dec, 2018)
  • [논문] 김홍표, 박혜진, 조남기, 이필준, Aquaporin 11-Dependent Inhibition of Proliferation by Deuterium Oxide in Activated Hepatic Stellate Cells. , Molecules , Vol.12 , No.12 , pp.3209 -3218 (Dec, 2018)
국제학술논문지
  • [논문] 김형수, 김홍표, 노민수, 안성진, 공준표, 안성찬, 표정주, 정다람, 이주창, 황석영, 신일진, 김정민, 2-Phenyl-8-(1-phenylallyl)-chromenone compounds have a pan-PPAR modulator pharmacophore , BIOORGANIC & MEDICINAL CHEMISTRY , Vol.27 , No.13 , pp.2948 -2958 (Jul, 2019)
  • [논문] 백승훈, 이동주, 김홍표, 정혜경, Structure analysis and antioxidant activities of an amylopectin-typepolysaccharide isolated from dried fruits of Terminalia chebula , CARBOHYDRATE POLYMERS , pp.100 -108 (May, 2019)
  • [논문] 윤태종, 박상규, 류지연, 박혜선, 이한아름, 홍신희, 홍관수, 김홍표, 조은이, Lechitin nano-liposomal particle as a CRISPR/Cas9 complex delivery system for treating type 2 diabetes , Journal of Nanobiotechnology , pp.19 -31 (Jan, 2019)
  • [논문] 이동주, 김형수, 유희선, 김석호, 김홍표, DDQ-Promoted Mild and Efficient Metal-Free Oxidative α-Cyanation of N-Acyl/Sulfonyl 1,2,3,4-Tetrahydroisoquinolines , MOLECULES , Vol.23 , No.12 , pp.3223 -3235 (Dec, 2018)
  • [논문] 김홍표, 박혜진, 조남기, 이필준, Aquaporin 11-Dependent Inhibition of Proliferation by Deuterium Oxide in Activated Hepatic Stellate Cells. , Molecules , Vol.12 , No.12 , pp.3209 -3218 (Dec, 2018)
  • [논문] 김홍표, 박혜진, 조남기, 이필준, 3,5-Diethoxy-3'-Hydroxyresveratrol (DEHR) Ameliorates Liver Fibrosis via Caveolin-1 Activation in Hepatic Stellate Cells and in a Mouse Model of Bile Duct Ligation Injury , MOLECULES , Vol.11 , pp.2833 -2841 (Oct, 2018)
  • [논문] 김홍표, 박재우, 최우균, 이필준, 정수월, 백승훈, 정헌택, 조성찬, 김종헌, 강병헌, 김형수, 김병삼, The novel resveratrol derivative 3,5-diethoxy-3',4'-dihydroxy-trans-stilbene induces mitochondrial ROS-mediated ER stress and cell death in human hepatoma cells in vitro. , ACTA PHARMACOLOGICA SINICA , Vol.38 , No.11 , pp.1486 -1500 (Nov, 2017)
  • [논문] 김홍표, 김정화, 성상현, Kim HW, Park SW, 김태범, Hepatoprotective Flavonoids in Opuntia ficus-indica Fruits by Reducing Oxidative Stress in Primary Rat Hepatocytes. , PHARMACOGNOSY MAGAZINE , Vol.13 , No.51 , pp.472 -476 (Jul, 2017)
  • [논문] 김홍표, 성상현, 김정화, Cytotoxic pterosins from Pteris multifida roots against HCT116 human colon cancer cells. , BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , Vol.27 , No.14 , pp.3144 -3147 (Jul, 2017)
  • [논문] 김홍표, 김정화, 성상현, 김현우, 양희정, Lignans from Opuntia ficus-indica seeds protect rat primary hepatocytes and HepG2 cells against ethanol-induced oxidative stress. , BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY , Vol.81 , No.1 , pp.181 -183 (Jan, 2017)
  • [논문] 김홍표, 성상현, 지준구, 이필준, 우승제, Bisdemethoxycurcumin Induces Apoptosis in Activated Hepatic Stellate Cells via Cannabinoid Receptor 2 , MOLECULES , Vol.20 , No.1 , pp.1277 -1292 (Jan, 2015)
  • [논문] 김홍표, 조남기, 이희경, 성상현, 김현우, 이종환, 김영중, 전병주, The effects of Betula platyphylla bark on amyloid beta-induced learning and memory impairment in mice , FOOD AND CHEMICAL TOXICOLOGY , Vol.74C , pp.156 -163 (Dec, 2014)
  • [논문] 김홍표, 김혜령, 홍민지, 양민혜, 김진웅, 유헌승, 양희정, 박정일, 성상현, 정종혜, 김정화, Stereoisomer-specific anti-cancer activities of ginsenoside Rg3 and Rh2 in hepG2 cells: disparity in cytotoxicity and autophagy-inducing effects by their 20(S)-epimers , BIOLOGICAL & PHARMACEUTICAL BULLETIN , Vol.37 , No.12 , pp.11 -17 (Dec, 2014)
  • [논문] 김홍표, 김형수, 서승룡, 이필준, 신일진, Upregulation of both heme oxygenase-1 and ATPase inhibitory factor 1 renders tumoricidal activity by synthetic flavonoids via depleting cellular ATP , BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , Vol.24 , No.20 , pp.4845 -4849 (Oct, 2014)
  • [논문] 김홍표, Choi AMK, Ryter SW, Profibrogenic phenotype in caveolin-1 deficiency via differential regulation of STAT-1/3 proteins , BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE , Vol.92 , No.5 , pp.370 -378 (Oct, 2014)
  • [논문] 김홍표, Lightening up Light Therapy: Activation of Retrograde Signaling Pathway by Photobiomodulation , BIOMOLECULES & THERAPEUTICS , Vol.22 , No.6 , pp.491 -496 (Sep, 2014)
  • [논문] 김홍표, Ryter, Stefan, 정헌택, Heme Oxygenase-1 as a Novel Metabolic Player , OXIDATIVE MEDICINE AND CELLULAR LONGEVITY , Vol.2013 , pp.814058-1 -814058-2 (Dec, 2013)
  • [논문] Choi, Augustine MK, Biswal SS, Cloonan, SM, Bhashyam, AR, Haspel, JA, Ryter, Stefan, Mizumura K, Singh A, Yao H, Cervo M, Sathirapongsasuti JF, An CH, Shan B, Franks JM, Haley KJ, Owen CA, Tesfaigzi Y, Washko GR, Quackenbush J, Silverman EK, Rahman I, Mahmood A, 김홍표, Lam, Hilaire, Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction , JOURNAL OF CLINICAL INVESTIGATION , Vol.123 , No.12 , pp.5212 -5230 (Dec, 2013)
  • [논문] 성상현, 조남기, 양희정, 허정무, 김현우, 김홍표, 이미나, Neuroprotective Benzyl Benzoate Glycosides from Disporum viridescens Roots in HT22 Hippocampal Neuronal Cells. , JOURNAL OF NATURAL PRODUCTS , Vol.76 , No.12 , pp.2291 -2297 (Nov, 2013)
  • [논문] 김홍표, Zhang, JL, Choi, Augustine MK, 이선진, Mitochondrial dysfunction induces formation of lipid droplets as a generalized response to stress. , OXIDATIVE MEDICINE AND CELLULAR LONGEVITY , Vol.2013 , pp.327167-1 -327168-10 (Sep, 2013)
  • [논문] 성성현, Lee M, Lee SH, Yang H, 정은주, 김영중, 김홍표, Kang J, Salicortin-Derivatives from Salix pseudo-lasiogyne Twigs Inhibit Adipogenesis in 3T3-L1 Cells via Modulation of C/EBPα and SREBP1c Dependent Pathway , MOLECULES , Vol.18 , No.9 , pp.10484 -10496 (Aug, 2013)
  • [논문] 성상현, 조남기, 이기용, Choi JH, 양희정, 정은주, 김홍표, 허정무, Cognitive-enhancing effects of Rhus verniciflua bark extract and its active flavonoids with neuroprotective and anti-inflammatory activities. , FOOD AND CHEMICAL TOXICOLOGY , Vol.58 , pp.355 -361 (Aug, 2013)
  • [논문] 성상현, 이기용, 전병준, 정은주, 김태범, 조남기, 허정무, 김홍표, 김승현, Cognition-enhancing and neuroprotective activities of the standardized extract of Betula platyphylla bark and its major diarylheptanoids. , PHYTOMEDICINE , pp.1315 -1320 (Nov, 2012)
  • [논문] 김홍표, 김영중, 정은주, 양혜경, 이필준, Selective apoptosis in hepatic stellate cells mediates the antifibrotic effect of phenanthrenes from Dendrobium nobile. , PHYTOTHERAPY RESEARCH , pp.974 -980 (Jul, 2012)
  • [논문] 정헌택, 장밍, 이그나로, 김슬기, 조연수, 조홍래, 김홍표, 백승훈, Sensing endoplasmic reticulum stress by protein kinase RNA-like endoplasmic reticulum kinase promotes adaptive mitochondrial DNA biogenesis and cell survival via heme oxygenase-1/carbon monoxide activity. , FASEB JOURNAL , pp.2558 -2568 (Jun, 2012)
  • [논문] 최명근, 다나카, 라이터, 스톨즈, 장멍, 이선진, 김홍표, 진양, Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death , AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY , pp.507 -514 (Apr, 2012)
  • [논문] 마크 페렐라, 정수월, 정헌택, 강영호, 이선진, 김홍표, 권민영, Transforming growth factor-β1 suppression of endotoxin-induced heme oxygenase-1 in macrophages involves activation of Smad2 and downregulation of Ets-2. , JOURNAL OF CELLULAR PHYSIOLOGY , pp.351 -360 (Jan, 2012)
  • [논문] Choi AMK, Lee SJ, Nakahira K, Jin-Fu Xu, 김영삼, 김홍표, Ryter SW, Carbon monoxide activates autophagy via mitochondrial reactive oxygen species formation , AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY , Vol.45 , No.4 , pp.867 -873 (Oct, 2011)
  • [논문] Choi AMK, Lee SJ, Ryter SW, 김홍표, Jin Y, Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis , AUTOPHAGY , Vol.7 , No.8 , pp.829 -839 (Aug, 2011)
  • [논문] Ryter SW, Wang X, Choi AMK, Lee SJ, 김홍표, Wang Y, Carbon monoxide inhibits Fas activating antibody-induced apoptosis in endothelial cells , MEDICAL GAS RESEARCH , pp.1 -11 (May, 2011)
  • [논문] Choi AMK, Nakahira K, Haspel JA, Fitzgerald KA, Ryter SW, Lee SJ, Cernadas M, Rabinovitch M, Englert JA, Lam HC, Dolinay T, 김홍표, Rathinam VA, Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome , NATURE IMMUNOLOGY , Vol.12 , No.3 , pp.222 -230 (Mar, 2011)
  • [논문] Choi AMK, Guo L, Smith A, Ryter SW, Rabinovitch M, Feghali-Bostwick C, Jin Y, Ifedigbo E, Chen ZH, Liu X, Sawada H, Li M, Alastalo TP, 김홍표, Lee SJ, Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension , AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE , Vol.183 , No.3 , pp.649 -658 (Mar, 2011)
  • [논문] 김홍표, 백승훈, 정헌택, 우제문, Son Y, 배현옥, 정수월, Heme oxygenase-1 comes back to endoplasmic reticulum , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , Vol.404 , No.1 , pp.1 -5 (Jan, 2011)
  • [논문] Celed?n JC, Bush A, Soto-Quir?s ME, Weiss ST, Choi AMK, Avila L, Lasky-Su J, Rafaels N, Ruczinski I, Beaty TH, Mathias RA, Barnes KC, Wilk JB, O'Connor GT, Gauderman WJ, Vora H, Baurley JW, Gilliland F, Liang C, Sylvia JS, Klanderman BJ, Sharma SS, Himes BE, Bossley CJ, Israel E, Raby BA, 김홍표, Hunninghake GM, TSLP polymorphisms are associated with asthma in a sex-specific fashion. , ALLERGY , Vol.65 , No.12 , pp.1566 -1575 (Dec, 2010)
  • [논문] Choi AMK, Chen ZH, Lam HC, Jin Y, Harikrishnan Parameswaran, Jiaofei Cao, Seon-Jin Lee, Emeka Ifedigbo, 김홍표, Ryter SW, Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema. , PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , Vol.107 , No.44 , pp.18880 -18885 (Nov, 2010)
국내학술논문지
  • [논문] 김홍표, 김영중, Revisiting Hepatoprotective Natural Products from a Biological Point of View , NATURAL PRODUCT SCIENCES , Vol.17 , No.3 , pp.165 -174 (Sep, 2011)
국제학술발표
  • [학술회의] 김홍표, Y.Joe, H.Chung, M.Zheng, 박정우, Uddin, A functional link between heme oxgyenase-1 and tristetraprolin in the anti-inflammatory effects of nicotine , 8th International Conference on Heme oxygenases, bioiron and oxidative stress , pp.65 -65 (Oct, 2014)
  • [학술회의] 김홍표, 조연수, 우딘, 정헌택, 김현정, 첸, 박정우, 장밍, Tristetraproline mediates anti-inflammatory effect of carbon monoxide against DDS-induced colitis , 8th international conference on Heme oxygenases, bioiron and oxidative stress , pp.64 -64 (Oct, 2014)
  • [학술회의] 김홍표, 최광은, 우승제, 이필준, Accumulation of heme and lipid mobilization during early hibernation periods , 8th international conference on Heme oxygenases, bioiron and oxidative stress , pp.68 -68 (Oct, 2014)
국내학술발표
  • [학술회의] 김홍표, 이필준, 우승제, curcuminoids induce apoptosis of hepatic stellate cells via differential expression and protein interaction of cannabinoid 2 receptor , 한국생약학회 제 43회 정기총회 및 학술대회 (Dec, 2012)
저서 및 번역
  • [저서] 김홍표, 가장 먼저 증명한 것들의 과학 (Sep, 2018)
  • [저서] 김홍표, 물의 과학 (Aug, 2018)
  • [저서] 김홍표, 숫자로 풀어가는 생물학 이야기 (Jan, 2018)
  • [저서] 김홍표, 김홍표의 크리스퍼 혁명 (Nov, 2017)
  • [저서] 김홍표, 배현옥, 백승훈, 최혜선, 정수월, 정헌택, 조연수, 박정우, 신재균, Heme Biology (Aug, 2017)
  • [저서] 김홍표, Cells, Gels and the Engines of Life (Jan, 2017)
  • [저서] 김홍표, 먹고 사는 것의 생물학 (Dec, 2016)
  • [저서] 김홍표, From Fish to Philosopher (Mar, 2016)
  • [저서] 김홍표, 우리는 어떻게 태어나는가 (Aug, 2015)
  • [저서] 김홍표, 진화와 의학 (Apr, 2015)
  • [저서] 김홍표, Novum Organum (Jul, 2014)
  • [저서] 김홍표, The Expression of the Emotions in Man and Animal (May, 2014)
  • [저서] 김홍표, 제2의 뇌 (Nov, 2013)
  • [저서] 김홍표, 산소와 그 경쟁자들 (Sep, 2013)
  • [저서] 김홍표, 윤기동, 권용수, 송경식, 오좌섭, 이정규, 장대식, 장영표, 정길생, 안미정, 생약학요약집 (Oct, 2012)
  • [저서] 김홍표, 윤기동, 권용수, 송경식, 오좌섭, 이정규, 장대식, 장영표, 정길생, 안미정, 생약학 실습서 (Sep, 2012)
특허 및 기타
  • [특허] 김홍표, 이필준, 신일진, 김형수, 레스베라트톨 유도체를 유효성분으로 포함하는 간경화 또는 간섬유화 예방 또는 치료용 약학 조성물 (등록) (10-1632839) (Jun, 2016)
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