• 연구실 : 원천관 214
• 연구실 전화 : 2598
• 이메일 : hkang@ajou.ac.kr
• 연구관심분야 : 생체분자에 대한 질량/형태 선택적 레이저 분광학
• 홈페이지 : https://sites.google.com/a/ajou.ac.kr/bmsl/

• 2002.08 서울대학교 박사
• 1997.02 서울대학교 석사
• 1995.02 서울대학교 학사

Postdoc,  2005 - 2007, Pacific Northwest National Laboratory
Postdoc,  2003 - 2004, Laboratoire de Photophysique Moléculaire du CNRS 
                         (Laboratory of Molecular Photophysics of the CNRS)

Photophysics of biomolecular building blocks
Conformer-specific UV/IR spectroscopy of biological building blocks and bioactive molecules
Conformational isomerization of biomolecules
Analytical application of cryogenic ion spectroscopy

1. [논문] 권장한, 송경옥, 이민지, Kazuya Tsuruta, Masaaki Fujii, Shun-ichi Ishiuchi, 강혁, Cryogenic Ion Spectroscopy of a Singly Protonated Peptide DYYVVR: Locating Phosphorylation Sites of a Kinase Domain , JOURNAL OF PHYSICAL CHEMISTRY LETTERS , pp.7103 -7108 (Aug, 2020)
2. [논문] 손운용, 김정진, 전명원, Masaaki Fujii, Shun-Ichi Ishiuchi, Takuma Aoki, 강혁, Entropic Effect Makes a More Tightly Folded Conformer of a β-Amino Acid Less Stable: UV-UV Hole Burning and IR Dip Spectroscopy of L-β3-Homotryptophan by Laser Desorption Supersonic Jet Technique , PHYSICAL CHEMISTRY CHEMICAL PHYSICS , Vol.20 , No.30 , pp.19979 -19986 (Jul, 2018)
3. [논문] Avik Ranjan Sarkar, 허철호, Hardev Singh Virdi, 강혁, 김정진, 이효원, 김은진, 김환명, 강철훈, A cysteamine-selective two-photon fluorescent probe for ratiometric bioimaging , CHEMICAL COMMUNICATIONS , pp.A -D (Dec, 2014)
4. [논문] 강혁, Claude Dedonder-Lardeux, G?raldine F?raud, Christophe Jouvet, New Method for Double-Resonance Spectroscopy in a Cold Quadrupole Ion Trap and Its Application to UV?UV Hole-Burning Spectroscopy of Protonated Adenine Dimer , JOURNAL OF PHYSICAL CHEMISTRY LETTERS , Vol.5 , No.15 , pp.2760 -2764 (Jul, 2014)
5. [논문] 손운용, 김민호, 김상수, 박영동, 강혁, Solvent-assisted conformational isomerization and the conformationally-pure REMPI spectrum of 3-aminophenol , PHYSICAL CHEMISTRY CHEMICAL PHYSICS , Vol.13 , No.15 , pp.7037 -7042 (Apr, 2011)

1. [논문] 전효남, 권장한, 강혁, Ultraviolet photodissociation spectra of singlyprotonated hexapeptides DYYVVR, DYFVVR, and DFYVVRat room temperature , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , pp.777 -779 (Sep, 2023)
2. [논문] 안희준, NKENKU ANIMBOM BUMA CARL, 유영동, 강혁, 김유권, Understanding the pulsed laser-induced modificationprocesses of TiO2 nanomaterials in aqueous solution , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , pp.1 -11 (Apr, 2023)
3. [논문] Vinayak Juvekar, 이효원, 조명기, 강혁, 이동준, 송주만, 김환명, 제종태, A red-emissive two-photon fluorescent probe for mitochondrial sodium ions in live tissue , CHEMICAL COMMUNICATIONS , pp.8929 -8932 (Aug, 2021)
4. [논문] Vinayak Juvekar, 임창수, 강혁, 노충균, 송득화, 이동준, 김환명, 신성재, Near-Infrared Ratiometric Two-Photon Probe for pH Measurement in Human Stomach Cancer Tissue , ACS APPLIED BIO MATERIALS , pp.2135 -2141 (Mar, 2021)
5. [논문] Vinayak Juvekar, 임창수, 강혁, 박상준, 송경옥, 이동준, 김환명, An azo dye for photodynamic therapy that is activated selectively by two-photon excitation , CHEMICAL SCIENCE , pp.1 -8 (Jan, 2021)
6. [논문] 권장한, 송경옥, 이민지, Kazuya Tsuruta, Masaaki Fujii, Shun-ichi Ishiuchi, 강혁, Cryogenic Ion Spectroscopy of a Singly Protonated Peptide DYYVVR: Locating Phosphorylation Sites of a Kinase Domain , JOURNAL OF PHYSICAL CHEMISTRY LETTERS , pp.7103 -7108 (Aug, 2020)
7. [논문] 박상준, Yen Leng Pak, 강혁, 송경옥, 임유빈, 김환명, Jean Bouffard, 윤주영, Endoplasmic Reticulum-Targeted Ratiometric N-Heterocyclic Carbene Borane Probe for Two-Photon Microscopic Imaging of Hypochlorous Acid , ANALYTICAL CHEMISTRY , Vol.90 , No.21 , pp.12937 -12943 (Nov, 2018)
8. [논문] 손운용, 김정진, 전명원, Masaaki Fujii, Shun-Ichi Ishiuchi, Takuma Aoki, 강혁, Entropic Effect Makes a More Tightly Folded Conformer of a β-Amino Acid Less Stable: UV-UV Hole Burning and IR Dip Spectroscopy of L-β3-Homotryptophan by Laser Desorption Supersonic Jet Technique , PHYSICAL CHEMISTRY CHEMICAL PHYSICS , Vol.20 , No.30 , pp.19979 -19986 (Jul, 2018)
9. [논문] Mai Hoang Tran, 서은정, 강혁, Alka Mansukhani, Quynh-Anh T. Nguyen, 민수홍, 이욱진, 주일로, 최주영, 홍순선, 이상윤, NEDD4-induced degradative ubiquitination of phosphatidylinositol 4-phosphate 5-kinase a and its implication in breast cancer cell proliferation , JOURNAL OF CELLULAR AND MOLECULAR MEDICINE , Vol.22 , No.9 , pp.4117 -4129 (May, 2018)
10. [논문] 이상윤, 강혁, Nonresonant Contribution in Pump?Probe Transient Ion Signal of Adenine , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , Vol.39 , No.3 , pp.408 -410 (Feb, 2018)
11. [논문] 김유권, 김유나, 이규성, 강혁, Enhanced photoactivity of stable colloidal TiO2 nanoparticles prepared in water by nanosecond infrared laser pulses , KOREAN JOURNAL OF CHEMICAL ENGINEERING , Vol.34 , No.6 , pp.1822 -1826 (Apr, 2017)
12. [논문] 허철호, Avik Ranjan Sarkar, 강혁, 김정진, 정태성, 백성훈, 김환명, 묵인희, A quadrupolar two-photon fluorescent probe for in vivo imaging of amyloid-b plaques , CHEMICAL SCIENCE , pp.1 -7 (Apr, 2016)
13. [논문] Patrick S. Walsh, 강혁, Carl McBurney, Jacob C. Dean, Samuel H. Gellman, Timothy S. Zwier, Conformation-specific spectroscopy of capped Glutamine-containing peptides: Role of a single glutamine residue on peptide backbone preferences , PHYSICAL CHEMISTRY CHEMICAL PHYSICS , Vol.18 , No.16 , pp.11306 -11322 (Mar, 2016)
14. [논문] 정해준, 김정진, 강혁, Laser Desorption of Tryptophan from Tryptophan?HCl Salt on a Graphite Substrate , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , Vol.37 , No.3 , pp.394 -396 (Mar, 2016)
15. [논문] 이소영, 강혁, Quantum Mechanical Study on Hydrogen Bonds between 3-Aminophenol and CHxCl4???x (x?=?1, 2, 3): Effect of the Number of Halogen Atoms# , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , Vol.36 , No.3 , pp.752 -756 (Mar, 2015)
16. [논문] 이소영, 강혁, Quantum Mechanical Study on the Blue-Shifting Hydrogen-Bond between 3-Aminophenol and CHX3 (X = F, Cl) , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , Vol.36 , No.1 , pp.111 -116 (Jan, 2015)
17. [논문] Avik Ranjan Sarkar, 허철호, Hardev Singh Virdi, 강혁, 김정진, 이효원, 김은진, 김환명, 강철훈, A cysteamine-selective two-photon fluorescent probe for ratiometric bioimaging , CHEMICAL COMMUNICATIONS , pp.A -D (Dec, 2014)
18. [논문] 강혁, Claude Dedonder-Lardeux, G?raldine F?raud, Christophe Jouvet, New Method for Double-Resonance Spectroscopy in a Cold Quadrupole Ion Trap and Its Application to UV?UV Hole-Burning Spectroscopy of Protonated Adenine Dimer , JOURNAL OF PHYSICAL CHEMISTRY LETTERS , Vol.5 , No.15 , pp.2760 -2764 (Jul, 2014)
19. [논문] Mitsuhiko Miyazaki, 강혁, 송재규, 최창민, 한노수, Masaaki Fujii, 김남준, MODE-specific deactivation of adenine at the singlet excited states , JOURNAL OF CHEMICAL PHYSICS , Vol.139 , No.12 , pp.124311 -124311 (Sep, 2013)
20. [논문] 손운용, 강정석, 이소영, 강혁, Fluorescence excitation spectrum and solvent-assisted conformational isomerization (SACI) of jet-cooled acetaminophen , CHEMICAL PHYSICS LETTERS , Vol.581 , pp.36 -41 (Aug, 2013)
21. [논문] 정해준, 김환명, 허철호, Masaaki Fujii, Shun-ichi Ishiuchi, 손운용, 강혁, Gas-Phase Spectroscopy of Laser-Desorbed Acedan and Proline-Acedan , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , Vol.34 , No.8 , pp.2241 -2242 (Aug, 2013)
22. [논문] 손운용, 강정석, 이소영, Mitsuhiko Miyazaki, Shun-ichi Ishiuchi, 민아름, 최명룡, 강혁, Masaaki Fujii, Conformationally resolved spectra of Acetaminophen by UV-UV hole burning and IR dip spectroscopy in gas phase , PHYSICAL CHEMISTRY CHEMICAL PHYSICS , Vol.15 , No.3 , pp.957 -964 (Jan, 2013)
23. [논문] 손운용, 강성식, 박영동, 이소영, 조근진, 강혁, Solvent-Assisted Conformational Isomerization (SACI) of meta-Substituted Phenols: Tuning Relative Stability, Isomerization Barrier, and IVR Rate , CHEMICAL PHYSICS LETTERS , Vol.525 , pp.37 -43 (Feb, 2012)
24. [논문] 김남준, 강혁, 김형민, 안태규, 장진영, 허지영, 김성근, Femtosecond decay dynamics of intact adenine and thymine base pairs in supersonic jet , ChemPhysChem , Vol.12 , No.10 , pp.1935 -1939 (Jul, 2011)
25. [논문] 손운용, 김민호, 김상수, 박영동, 강혁, Solvent-assisted conformational isomerization and the conformationally-pure REMPI spectrum of 3-aminophenol , PHYSICAL CHEMISTRY CHEMICAL PHYSICS , Vol.13 , No.15 , pp.7037 -7042 (Apr, 2011)
26. [논문] Ivan Alata, 김민호, 김상수, 손운용, Alexander Patzer, Claude Dedonder-Lardeux, Markus Sch?tz, Michel Broquier, 강혁, Christophe Jouvet, Otto Dopfer, Microhydration effects on the electronic spectra of protonated polycyclic aromatic hydrocarbons: [naphthalene-(H2O)n = 1,2]H+ , JOURNAL OF CHEMICAL PHYSICS , Vol.134 , No.7 , pp.074037-1 -074307-7 (Feb, 2011)
27. [논문] 손운용, 김민호, 김상수, 강혁, Computational study of 3-aminophenol?(CO2)1 cluster: CO2 capture ability of 3-aminophenol , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , Vol.263 , No.10 , pp.2806 -2808 (Oct, 2010)
28. [논문] 김남준, 김성근, 안태규, 이상학, 장진영, 강혁, Excited state lifetime of adenine near the first electronic band origin , JOURNAL OF CHEMICAL PHYSICS , Vol.133 , pp.154311-1 -154311-4 (Oct, 2010)
29. [논문] 김민호, 김상수, 박영동, 강혁, REMPI and IR-UV double resonance spectroscopy of 3-aminophenol?(NH3)1 cluster in the gas phase , JOURNAL OF MOLECULAR SPECTROSCOPY , Vol.263 , No.1 , pp.51 -55 (Sep, 2010)
30. [논문] 호쑨흥, 강혁, 모선일, 장혜영, Electro-Organocatalysis: Enantioselective a-alkylation of aldehydes , EUROPEAN JOURNAL OF ORGANIC CHEMISTRY , pp.4436 -4441 (Jul, 2010)
31. [논문] 강혁, 김민호, 김상수, Effects of Amino Substitution on the Excited State Hydrogen Transfer in Phenol: A TDDFT Study , Bulletin of the Korean Chemical Society , Vol.30 , No.7 , pp.1481 -1484 (Jul, 2009)
32. [논문] Arzu Umar, 강혁, Annemieke M. Timmerm, John A. Foekens, John W. M. Martens, Ljiljana Pasa-Tolic, Marion E. Meijer-van, Maxime P. Look, Michael A. den Bakke, Navdeep Jaitly, Theo M. Luider, Identification of a Putative Protein Profile Associated with Tamoxifen Therapy Resistance in Breast Cancer , Molecular & Cellular Proteomics , Vol.8 , No.6 , pp.1278 -1294 (Jun, 2009)
33. [논문] 강혁, Transient Photoelectron Spectrum of NaI During Photodissociation at 307 nm , Bulletin of the Korean Chemical Society , Vol.30 , No.4 , pp.775 -776 (Apr, 2009)
34. [논문] 오한빈, 강혁, 박수진, 안화근, 이범구, 이선영, 이예원, 조기호, Electron Capture Dissociation of Proteins Initiated by Photoelectrons Generated from 266 nm UV Laser Radiation on an ICR Cell Wall , Bulletin of the Korean Chemical Society , Vol.29 , No.9 , pp.1673 -1677 (Sep, 2008)
35. [논문] Richard D. Smith, 강혁, Aleksey V. Tolmachev, Errol W. Robinson, Ljiljana Paša-T, Natacha M. Lourette, Si Wu, Trapped-Ion Cell with Improved DC Potential Harmonicity for FT-ICR MS , Journal of the American Society for Mass Spectrometry , Vol.19 , No.4 , pp.586 -597 (Apr, 2008)

1. [학술회의] 강혁, Spectroscopy of Consecutive Tyrosine Residues: Singly Protonated DYYVVR , Asia-Oceania Mass Spectrometry Conference (Aug, 2023)
2. [학술회의] 권장한, 강혁, 송경옥, 이민지, Kazuya Tsuruta, Shun-ichi Ishiuchi, Cryogenic Ion Spectroscopy of Singly Protonated Peptide DYYVVR for Identifying Phosphorylation Sites , The 6th Asian Workshop on Molecular Spectroscopy (Nov, 2022)
3. [학술회의] 강혁, Cryogenic Ion Spectroscopy of DYYVVR: Locating the Phosphorylation Site of a Janus Homology Domain , The 23rd East Asian Workshop on Chemical Dynamics (Sep, 2019)
4. [학술회의] 김유권, 강혁, Stable colloidal suspension of TiO2 nanoparticles in aqueous solution prepared by nanosecond laser pulses and their photocatalytic performances , 5th International Conference on Advanced Nanoparticle Generation and Excitation by Lasers in Liquids (ANGEL) , pp.P-II-4 (Jun, 2018)
5. [학술회의] 강혁, Non-Radiative Deactivation of Biological Building Blocks , The 21st East Asian Workshop on Chemical Dynamics (Dec, 2017)
6. [학술회의] 강혁, Novel double-resonance laser spectroscopy technique in a cold quadrupole ion trap and its application to protonated adenine dimer , Pacifichem2015 (Dec, 2015)
7. [학술회의] 강혁, Double Resonance Spectroscopy of Protonated Adenine Dimer in a Cold Quadrupole Ion trap , 19th East Asian Workshop on Chemical Dynamics (Oct, 2015)
8. [학술회의] 강혁, New UV-UV Hole Burning Spectroscopy Method in a Quadrupole Ion Trap and Its Application to Protonated Adenine Dimer , IUPAC 2015 (Aug, 2015)
9. [학술회의] 강혁, UV-UV HOLE-BURNING SPECTROSCOPY OF A PROTONATED ADENINE DIMER IN A COLD QUADRUPOLE ION TRAP , International Symposium on Molecular Spectroscopy (Jun, 2015)
10. [학술회의] 강혁, Solvent-Assisted Conformational Isomerization of Substituted Phenols and a New Method for Double Resonance Spectroscopy in a Quadrupole Ion Trap , Shining Light on Molecular Structure (Sep, 2014)
11. [학술회의] 강혁, REMPI and Double Resonance Spectroscopy of L-β-Homotryptophan in Gas Phase , IBBI 14 - Conference on Isolated Biomolecules and Biomolecular Interactions (May, 2014)
12. [학술회의] 강혁, Conformer-Specific Spectroscopy and Conformational Isomerization of Bio-Active Molecules , The 15th Asian Chemical Congress (Aug, 2013)
13. [학술회의] 강혁, Solvent-Assisted Conformational Isomerization of Acetamophen in the Gas Phase , Biological molecules in the gas phase and in solution (Jul, 2013)
14. [학술회의] 강혁, Solvent-Assisted Conformational Isomerization (SACI) of meta-Substituted Phenols: Tuning Relative Stability, Isomerization Barrier, and IVR Rate , The 16th East Asian Workshop on Chemical Dynamics (Apr, 2012)
15. [학술회의] 강혁, Solvent-Assisted Conformational Isomerization of Drugs and Neurotransmitters in the Gas Phase , Isolated Biomolecules and Biomolecular Interactions 2012 (Jan, 2012)
16. [학술회의] 강혁, Solvent-Assisted Conformational Isomerization (SACI) of meta-Substituted Phenols , 15th East Asian Workshop on Chemical Dynamics (May, 2011)
17. [학술회의] 강혁, REMPI and IR-UV double resonance spectroscopy of 3-aminophenol-ammonia cluster , Pacifichem2010 (Dec, 2010)
18. [학술회의] 강혁, Solvent-assisted conformational ionization of 3-aminophenol , Molecular and ionic clusters conference (Sep, 2010)
19. [학술회의] 강혁, REMPI and IR-UIV double resonance spectroscopy of 3-aminophenol-ammonia cluster , The 14th Ease Asian Workshop on Chemical Dynamics , pp.17 -18 (May, 2010)
20. [학술회의] 강혁, REMPI and IR-UV double resonance spectroscopy of aminophenol-ammonia clusters , Mini International Symposium on Molecular Science for Supra Functional Systems , pp.7 -8 (Jan, 2010)
21. [학술회의] 강혁, Christophe Jouvet, Gilles Gregoire, Ultrafast laser-induced dissociation of protonated tryptophan-leucine dipeptide , Korean-French Symposium on Chemical Dynamics , Vol.3 , No.1 , pp.24 -24 (Jul, 2008)
22. [학술회의] 강혁, C. Jouvet, G. Gregoire, Excited State Hydrogen Transfer in Protonated Amino Acids: An Ultrafast Non-Radiative Decay Pathway of Biological Molecules , Asian Conference on Ultrafast Phenomena , Vol.5 , No.1 , pp.22 -23 (Jan, 2008)

1. [학술회의] 권장한, 강혁, 전효남, UV photodissociation spectroscopy of protonated tyrosine at room temperature with a new QIT-TOF mass spectrometer , 대한화학회 제 130회 학술발표회 (Oct, 2022)
2. [학술회의] 권장한, 강혁, 송경옥, 전효남, Locating the Phosphorylation Site of a Janus Homology Domain by Cryogenic Ion Spectroscopy of Singly Protonated DYYVVR , 제134차 대한화학회 물리화학분과 여름 심포지엄 (Jul, 2021)
3. [학술회의] 공다인, 강혁, 김유권, Effect of Pulsed Laser Fluence on the Morphology of MoS2 Nanoparticles , 대한화학회 제127회 학술발표회 (Apr, 2021)
4. [학술회의] 전효남, 강혁, 권장한, Cryogenic Ion Spectroscopy of DYYVVR: Structural Assignment by IR Spectroscopy , 대한화학회 제127회 학술발표회 (Apr, 2021)
5. [학술회의] 송경옥, 강혁, 권장한, Cryogenic Ion Spectroscopy of DYYVVR: Structural Assignment by DFT Calculation , 대한화학회 제127회 학술발표회 (Apr, 2021)
6. [학술회의] 공다인, 강혁, 김유권, Pulsed laser-induced surface modification of TiO2 nanoparticles , 대한화학회 제125회 학술발표회 (Jul, 2020)
7. [학술회의] 권장한, 강혁, Construction of a New Quadrupole Ion Trap – Time of Flight Mass Spectrometer for Spectroscopy of Biomolecular Ions , 대한화학회 제125회 학술발표회 (Jul, 2020)
8. [학술회의] 안희준, 강혁, 김유권, 유영동, Observation of changes in the morphology and bulk phases of TiO2 nanoparticles under pulsed laser irradiation in water , 대한화학회 제123회 학술발표회 (Apr, 2019)
9. [학술회의] 김다연, 김유권, 강혁, 김정진, Environment-friendly synthesis of TiO2 nanoparticles in aqueous solution with a nanosecond infrared laser , 제117회 대한화학회 춘계학술대회 , pp.562 -562 (Apr, 2016)
10. [학술회의] 강혁, Solvent-Assisted Conformational Isomerization (SACI) of Bio-active Molecules , 112차 대한화학회 물리화학분과회 심포지엄 (Mar, 2013)
11. [학술회의] 강혁, Targeted Tandem Mass Spectrometry for High-Throughput Comparative Proteomics employing nano-LC coupled with FTICR MS , 대한화학회 제102회 총회 및 학술발표회 , Vol.102 , No.2 , pp.862 -862 (Oct, 2008)
12. [학술회의] 강혁, An alternative approach to shot-gun proteomics: targeted MS/MS for high-throughput comparative proteomics and potential biomarker discovery , 한국질량분석학회 2008 여름정기학술대회 , Vol.2008 , No.1 , pp.47 -47 (Aug, 2008)
13. [학술회의] 강혁, Christophe Jouvet`, Gilles Gregoire, Ergodic vs. non-ergodic pathways during laser-induced dissociation of protonated tryptophan-leucine dipeptide , 대한화학회 제101회 총회 및 학술발표회 , Vol.101 , No.1 , pp.259 -259 (Apr, 2008)
14. [학술회의] 강혁, Excited State Hydrogen Transfer in Protonated Amino Acids: An Ultrafast Non-Radiative Decay Pathway of Biological Molecules , 2007년 제3차 대한화학회 물리분과회 , Vol.0 , No.0 , pp.2 -2 (Sep, 2007)

1. [저서] 안영환, 강혁, 김상인, 김성환, 박지용, 염동일, 이상운, 이순일, 하나영, 허준석, 차세대 박막형 태양전지 연구 동향 (Jun, 2017)