- About Ajou
- Admission
- Academics
- Research
-
International
International
- Campus Life
-
News and Event
News and Event
-
AUT
AUT
Ajou News
NEW (2016.04.11)A team led by Professor Hwan Myung Kim publishes the third paper in The Chemical Science, a renowned journal
- 2016-04-26
- 25391
A team led by Ajou's Professor Hwan Myung Kim publishes the third paper in The Chemical Science, a renowned journal in chemistry
[2016.04.11]
A research paper authored by the team of Ajou University Professor Hwan Myung Kim (Department of Chemistry, Department of Energy System Research of the Graduate School) was published on April 7th in the online edition of The Chemical Science, which is issued by the Royal Society of Chemistry of the U.K.
Cheol Ho Huh (doctoral course), Sang Jun Park (combined master's and doctorate program), and Avik Sarkar (postdoctoral course) worked together as the first authors for the paper, which is entitled "A Ratiometric Two-Photon Probe for Quantitative Imaging of Mitochondrial pH Values."
'A two-photon fluorescent probe' is a next-generation imaging material that can detect the quantity of different chemical species within organisms in real time. The results can be used in a precise diagnosis. Existing fluorescent probes use short wavelength light with high energy level (ultraviolet rays - visible rays) as the excitation source. That can cause damage to organism samples and allow for observing only the surface of tissues because the light cannot penetrate deep into them. The two-photon fluorescent probe, however, uses infrared rays with lower energy levels and deep penetration capability, which allows for observing inside the tissues of live organisms at the sub-cellular level through three-dimensional high-definition imaging.
Professor Kim's team earlier published two papers on February 23th and October 27th last year in The Chemical Science, which is an influential journal in chemistry with an Impact Factor of 9.211 in 2014. The papers are entitled "A Quadrupolar Two-Photon Fluorescent Probe for In Vivo Imaging of Amyloid-β Plaques" and "A Carboxylesterase-Selective Ratiometric Fluorescent Two-Photon Probe and Its Application to Hepatocytes and Liver Tissues," respectively.
Professor Kim said, "My team is currently conducting research on applying 'two-photon fluorescent probes' to the precise diagnosis and treatment of diseases," adding, "I plan to focus on developing various imaging materials and innovative and advanced diagnosis platforms."
The research was conducted with the support of the Progressive Research Project and the Priority Research Institutes Project, which are carried out by the Ministry of Science, ICT, and Future Planning.