환경안전공학과

연구성과

• Kim HJ, Kim YH, Shin JH, Shashi KB, Seo HM, Choi KY, ParK KM, and Yang YH, “Optimization of direct lysine decarboxylase biotransformation for cadaverine production with whole cell biocatalysts at high substrate concentration”, Journal of Microbiology and Biotechnology, Feb, 2015
• Ko SK, Choi KY*, Yang YH, and Kim BG, “Rational design and directed evolution of CYP102A1 (BM3) for regio-specific hydroxylation of isoflavone”, Biotechnology and Bioprocess Engineering, 2015
• Yang YH, Kim BG, Choi KY*, “Synthesis of 3’-ortho-dihydroxy isoflavone by regio-selectivity driven evolution of CYP102D1”, Enzyme and Microbial Technology, April, 2015
• Kim HJ, Choi YK, Jeon HJ, Shashi KB, Kim YH, Kim YG, Choi KY, Kim HJ, Lee SH, Lee YK, and Yang YH, “Growth-promotion of Chlorella vulgaris by modification of nitrogen source composition with symbiotic bacteria, Microbacterium sp. HJ1 Biomass and Bioen”, April, 2015
• Jung E, Choi KY, Jung DH, Yun HD, Kim BG, “Hydroxylation of Mammalian Lignan Enterodiol by Cytochrome P450s in Actinomycetes sp., Korean Journal of Chemical Engineering, 32(3);471-477,2015
• Kim YH, Park BS, Bhaia SK, Seo HM, Jeon JM, Kim HJ, Yi DH, Choi KY, Park HY, Yang YH, “ Production of rapamycin in Streptomyces hygroscopicus from glycerol based media optimization by systemic methodology”, J Microbiol Biotechnol, 24(10):1319-1326 ,2014
• Choi KY*, Jung EO, Yang YH, Hyungdon Yun, and Kim BG, “Engineering class I cytochrome P450s by gene fusion with NADPH-dependent reductase and S. avermitilis host development for daidzein biotransformation”, Applied Microbiology and Biotechnology, 98(19):8191-200, 2014
• Choi KY*, David G. Wernick, Christine A. Tat and James C. Liao, “Consolidated conversion of protein waste into biofuels and ammonia using Bacillus subtilis”, Metabolic Engineering,23:53-61, 2014
• Pandey BP, Lee N, Choi KY, Kim JW, Kim EJ and Kim BG, “Identification of electron transfer protein ferredoxin and ferredoxin reductase for CYP105D7 activity towards dadizein from Streptomyces avermitilis MA4680”, Applied Microbiology and Biotechnology, 98(11):5009-17, 2014
• Rajesh T, Jeon JM, Song E, Park HM, Seo HM, Kim HJ, Yi DH, Kim YH, Choi KY, Kim YG, Park HY, Lee YK, Yang YH, “Putative role of a Streptomyces coelicolor-derived α-mannosidase in deglycosylation and antibiotic production”, Applied Biochemistry and Biotechnology, Feb , 172(3):1639-51, 2014
• David G. Wernick, Choi KY, Christine A. Tat, Jimmy G. La Fontaine Rivera, and James C. Liao, “The extreme obligate alkaliphile Bacillus marmarensis DSM21297: Genome sequence and characterization reveal its application for ammonia reclamation and biorefining”, Genome Announcements (ASM), 27;1(6), 2013
• Rajesh T, Kim YH, Choi YK, Jeon JM, Kim HJ, Park SH, Park HY, ChoiKY, Kim H, Kim HJ, Lee SH, and Yang YH, “Identification of functional characterization of an α-amylase with broad temperature and pH stability from Paenibacillus sp.”, Applied Biochemistry and Biotechnology, May; 170(2):359-69, 2013
• Jeon JM, Choi HW, Yoo GC, Rajesh T, Choi YK, Choi KY, Park HY, Park SH, Kim YG, Kim HJ, Lee SH and Yang YH, “New mixture composition of organic solvents for efficient extraction of lipids from Chlorella vulgaris”, Biomass & Bioenergy, Dec;59:279-284, 2013
• Rajesh T, Jeon JM, Kim YH, Ki, HJ, Yi DH, Park SH, Choi KY, Kim YG, Kim J, Jung S, Park HY and Yang YH, “Functional analysis of the gene SCO1782 encoding Streptomyces hemolysin (S-hemolysin) in Streptomyces coelicolor M145”, Toxicon, Sep;71:159-65, 2013
• Choi KY*, Jung EO, Yang YH, Romas J. Kazlauskas and Kim BG, “Development of colorimetric HTS assay of cytochrome P450 for ortho-specific hydroxylation and engineering of CYP102D1 with enhanced catalytic activity and regioselectivity”, ChemBioChem, Jul 8;14(10):1231-8, 2013
• Choi KY*, Jung EO, Yang YH, Kim BG, “Production of a novel O-methyl-isoflavone by regioselective sequential hydroxylation and O-methylation reactions in Streptomyces avermitilis host system.” Biotechnology and Bioengineering, 110(10), 2591-99, 2013
• Rajesh T, Sung C, Kim H, Song E, Park HY, Jeon JM, Yoo D, Kim HJ, Kim YH, Choi KY, Song KG and Yang YH, “Phosphorylation of chloroamphenicol by a recombinant protein Yhr2 from Streptomyces avermitilis MA4680”, Bioorganic & Medicinal Chemistry Letters, June 15;23(12):3614-9, 2013
• Rajesh T, Kim YH, Choi YK, Jeon JM, Kim HJ, Park SH, Park HY, Choi KY, Kim H, Kim HJ, Lee SH, Yang YH, “Identification and Functional Characterization of an α-Amylase with Broad Temperature and pH Stability from Paenibacillus sp.”, Applied Biochemistry and Biotechnology, May; 170(2):359-369, 2013
• Song E, Rajesh T, Lee BR, Kim EJ, Jeon JM, Park SH, Park HY, Choi KY, Kim YG, Yang YH, Kim BG, “Deletion of an architectural unit, leucyl aminopeptidase (SCO2179), in Streptomyces coelicolor increases actinorhodin production and sporulation.”, Applied Microbiology and Biotechnology, Aug;97(15):6823-33, 2013
• Choi KY*, KimHJ,JungDH,JungJY,JungE,YangYH,KimBG,OhMK,“Transcriptomic study for screening genes involved in the oxidative bioconversions of Streptomyces avermitilis.”, Bioprocess Biosystems Engineering, Mar 9, On-line published, 2013(contributed equally)
• Jung DH, Choi W, Choi KY, Jung E, Yun H, Kazlauskas RJ, Kim BG, “Bioconversion of p-coumaric acid to p-hydroxystyrene using phenolic acid decarboxylase from B. amyloliquefaciens in biphasic reaction system.”, Applied Microbiology and Biotechnology. Feb;97(4):1501-11, 2013
• Choi KY*, Jung E, Jung DH, Pandey BP, Lee N, Yun H, Park HYand Kim BG, “Novel iron-sulfur containing NADPH-reductase from Nocardia farcinica IFM10152 and fusion construction with CYP51 lanosterol demethylase”, Biotechnology and Bioengineering, 109(3):630-636, 2012
• Choi KY*, Jung E, Jung DH, Park HY and Kim BG, “Engineering of daidzein 3’-hydroxylase P450 enzyme into catalytically artificial self-sufficient CYP”, Microbial Cell Factories, 11(81), 2012
• Choi KY*, Jung E, Jung DH, Park HY, Lee N and Kim BG, “Cloning, expression and characterization of CYP102D1, a self-sufficient P450 monooxygenases from Streptomyces avermitilis”, FEBS Journal, 279(9):1650-1662, 2012
• Pandey BP, Lee N, Choi KY, Jung E, Jeong DH and Byung-Gee Kim "Screening of Bacterial Cytochrome P450s responsible for regiospecific hydroxylation of (iso)flavonoids" Enzyme and Microbial Technology. 48(4-5):386-392, 2011
• Chung YH, Song JW, Choi KY, Yoon JW, Yang KM and Park JB, “Cloning, Expression, and Characterization of P450 Monooxygenase CYP102H1 from Nocardia farcinica”, Journal of The Korean Society for Applied Biological Chemistry, 55(2):386-392, 2011
• Pandey BP, Roh C, Choi KY, Lee N, Kim EJ, Ko S, Kim T, Yun H and Kim BG, “Regioselective Hydroxylation of Daidzein Using P450 (CYP105D7) from Streptomyces avermitilis MA4680", Biotechnology and Bioengineering, 105(4):697-704, 2010
• Park JS, Kim DH, Shim JS, Kim JS, Choi KY, Kim BG, Kim DH and Kim HK, "7,8,4'-Trihydroxyisoflavone from Fermented Soybean Food and Its Biological Activity" J.Soc.Cosmet. Scientists Korea, 36(3):221-226, 2010
• Choi KY*, Park HY, Kim BG. "Characterization of bi-functional CYP154 from Nocardia farcinica IFM10152 in the O-dealkylation and ortho-hydroxylation of formononetin", Enzyme and Microbial Technology 47(7):327-334, 2010
• Choi KY*, Kim TJ, Koh SK, Roh CH, Pandey BP, Lee N, Kim BG, "A-ring ortho-specific monohydroxylation of daidzein by cytochrome P450s of Nocardia farcinica IFM10152" Biotechnology journal, 4(11):1586-1595, 2009
• Roh C, Choi KY, Pandey BP, Kim BG, "Hydroxylation of daidzein by CYP107H1 from Bacillus subtilis 168" Journal of Molecular Catalysis B: Enzymatic, 59:248-253, 2009
• Roh C. Seo SH, Choi KY, Cha M, Pandey BP, Kim JH, Park JS, Kim DH, Chang IS and Kim BG, "Regioselective hydroxylation of isoflavones by Streptomyces avermitilis MA-4680" The Journal of Bioscience and Bioengineering, 108(1):41-46, 2009